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Clinically relevant aberrant Filip1l DNA methylation detected in a murine model of cutaneous squamous cell carcinoma

BACKGROUND: Cutaneous squamous cell carcinomas (cSCC) are among the most common and highly mutated human malignancies. Understanding the impact of DNA methylation in cSCC may provide avenues for new therapeutic strategies. METHODS: We used reduced-representation bisulfite sequencing for DNA methylat...

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Detalles Bibliográficos
Autores principales: Roth, Kevin, Coussement, Louis, Knatko, Elena V., Higgins, Maureen, Steyaert, Sandra, Proby, Charlotte M., de Meyer, Tim, Dinkova-Kostova, Albena T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138604/
https://www.ncbi.nlm.nih.gov/pubmed/34000624
http://dx.doi.org/10.1016/j.ebiom.2021.103383