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Clinically relevant aberrant Filip1l DNA methylation detected in a murine model of cutaneous squamous cell carcinoma
BACKGROUND: Cutaneous squamous cell carcinomas (cSCC) are among the most common and highly mutated human malignancies. Understanding the impact of DNA methylation in cSCC may provide avenues for new therapeutic strategies. METHODS: We used reduced-representation bisulfite sequencing for DNA methylat...
Autores principales: | Roth, Kevin, Coussement, Louis, Knatko, Elena V., Higgins, Maureen, Steyaert, Sandra, Proby, Charlotte M., de Meyer, Tim, Dinkova-Kostova, Albena T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138604/ https://www.ncbi.nlm.nih.gov/pubmed/34000624 http://dx.doi.org/10.1016/j.ebiom.2021.103383 |
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