In vivo library screening identifies the metabolic enzyme aldolase A as a promoter of metastatic lung colonization

Elucidations of the factors that promote the growth of disseminated tumor cells (DTCs) into life-threatening lesions stand to provide much needed prognostic and therapeutic targets of translational utility for patients with metastatic cancer. To identify such regulators, we conducted gain-of-functio...

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Detalles Bibliográficos
Autores principales: Tu, Zhenbo, Hou, Shengqi, Zheng, Yurong, Abuduli, Maerjianghan, Onder, Tamer, Intlekofer, Andrew M., Karnoub, Antoine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138724/
https://www.ncbi.nlm.nih.gov/pubmed/34036247
http://dx.doi.org/10.1016/j.isci.2021.102425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138724/
https://www.ncbi.nlm.nih.gov/pubmed/34036247
http://dx.doi.org/10.1016/j.isci.2021.102425

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