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In vivo library screening identifies the metabolic enzyme aldolase A as a promoter of metastatic lung colonization
Elucidations of the factors that promote the growth of disseminated tumor cells (DTCs) into life-threatening lesions stand to provide much needed prognostic and therapeutic targets of translational utility for patients with metastatic cancer. To identify such regulators, we conducted gain-of-functio...
Autores principales: | Tu, Zhenbo, Hou, Shengqi, Zheng, Yurong, Abuduli, Maerjianghan, Onder, Tamer, Intlekofer, Andrew M., Karnoub, Antoine E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138724/ https://www.ncbi.nlm.nih.gov/pubmed/34036247 http://dx.doi.org/10.1016/j.isci.2021.102425 |
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