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The small molecule DIPQUO promotes osteogenic differentiation via inhibition of glycogen synthase kinase 3-beta signaling

Bone fractures are common impact injuries typically resolved through natural processes of osteogenic regeneration and bone remodeling, restoring the biological and mechanical function. However, dysfunctionality in bone healing and repair often arises in the context of aging-related chronic disorders...

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Detalles Bibliográficos
Autores principales: Cook, Brandoch, Walker, Nicholas, Zhang, Qisheng, Chen, Shuibing, Evans, Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138761/
https://www.ncbi.nlm.nih.gov/pubmed/33895139
http://dx.doi.org/10.1016/j.jbc.2021.100696