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Defining steps in RAVE-catalyzed V-ATPase assembly using purified RAVE and V-ATPase subcomplexes

The vacuolar H(+)-ATPase (V-ATPase) is a highly conserved proton pump responsible for the acidification of intracellular organelles in virtually all eukaryotic cells. V-ATPases are regulated by the rapid and reversible disassembly of the peripheral V(1) domain from the integral membrane V(o) domain,...

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Detalles Bibliográficos
Autores principales: Jaskolka, Michael C., Tarsio, Maureen, Smardon, Anne M., Khan, Md. Murad, Kane, Patricia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138766/
https://www.ncbi.nlm.nih.gov/pubmed/33895134
http://dx.doi.org/10.1016/j.jbc.2021.100703