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A Chemical Acetylation-Based Mass Spectrometry Platform for Histone Methylation Profiling

Histones are highly posttranslationally modified proteins that regulate gene expression by modulating chromatin structure and function. Acetylation and methylation are the most abundant histone modifications, with methylation occurring on lysine (mono-, di-, and trimethylation) and arginine (mono- a...

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Detalles Bibliográficos
Autores principales: Zappacosta, Francesca, Wagner, Craig D., Della Pietra, Anthony, Gerhart, Sarah V., Keenan, Kathryn, Korenchuck, Susan, Quinn, Chad J., Barbash, Olena, McCabe, Michael T., Annan, Roland S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138768/
https://www.ncbi.nlm.nih.gov/pubmed/33775892
http://dx.doi.org/10.1016/j.mcpro.2021.100067