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A Chemical Acetylation-Based Mass Spectrometry Platform for Histone Methylation Profiling
Histones are highly posttranslationally modified proteins that regulate gene expression by modulating chromatin structure and function. Acetylation and methylation are the most abundant histone modifications, with methylation occurring on lysine (mono-, di-, and trimethylation) and arginine (mono- a...
Autores principales: | Zappacosta, Francesca, Wagner, Craig D., Della Pietra, Anthony, Gerhart, Sarah V., Keenan, Kathryn, Korenchuck, Susan, Quinn, Chad J., Barbash, Olena, McCabe, Michael T., Annan, Roland S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138768/ https://www.ncbi.nlm.nih.gov/pubmed/33775892 http://dx.doi.org/10.1016/j.mcpro.2021.100067 |
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