Evaluating assembly and variant calling software for strain-resolved analysis of large DNA viruses

Infection with human cytomegalovirus (HCMV) can cause severe complications in immunocompromised individuals and congenitally infected children. Characterizing heterogeneous viral populations and their evolution by high-throughput sequencing of clinical specimens requires the accurate assembly of ind...

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Detalles Bibliográficos
Autores principales: Deng, Zhi-Luo, Dhingra, Akshay, Fritz, Adrian, Götting, Jasper, Münch, Philipp C, Steinbrück, Lars, Schulz, Thomas F, Ganzenmüller, Tina, McHardy, Alice C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Problem Solving Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138829/
https://www.ncbi.nlm.nih.gov/pubmed/34020538
http://dx.doi.org/10.1093/bib/bbaa123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138829/
https://www.ncbi.nlm.nih.gov/pubmed/34020538
http://dx.doi.org/10.1093/bib/bbaa123

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