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Evaluating assembly and variant calling software for strain-resolved analysis of large DNA viruses
Infection with human cytomegalovirus (HCMV) can cause severe complications in immunocompromised individuals and congenitally infected children. Characterizing heterogeneous viral populations and their evolution by high-throughput sequencing of clinical specimens requires the accurate assembly of ind...
Autores principales: | Deng, Zhi-Luo, Dhingra, Akshay, Fritz, Adrian, Götting, Jasper, Münch, Philipp C, Steinbrück, Lars, Schulz, Thomas F, Ganzenmüller, Tina, McHardy, Alice C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138829/ https://www.ncbi.nlm.nih.gov/pubmed/34020538 http://dx.doi.org/10.1093/bib/bbaa123 |
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