Antibody Format and Serum Disposition Govern Ocular Pharmacokinetics of Intravenously Administered Protein Therapeutics

Protein therapeutics have witnessed tremendous use and application in recent years in treatment of various diseases. Predicting efficacy and safety during drug discovery and translational development is a key factor for successful clinical development of these therapies. In general, drug related tox...

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Detalles Bibliográficos
Autores principales: Shivva, Vittal, Boswell, C. Andrew, Rafidi, Hanine, Kelley, Robert F., Kamath, Amrita V., Crowell, Susan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138871/
https://www.ncbi.nlm.nih.gov/pubmed/34025395
http://dx.doi.org/10.3389/fphar.2021.601569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138871/
https://www.ncbi.nlm.nih.gov/pubmed/34025395
http://dx.doi.org/10.3389/fphar.2021.601569

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