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Spatial density of open chromatin: an effective metric for the functional characterization of topologically associated domains

Topologically associated domains (TADs) are spatial and functional units of metazoan chromatin structure. Interpretation of the interplay between regulatory factors and chromatin structure within TADs is crucial to understand the spatial and temporal regulation of gene expression. However, a computa...

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Detalles Bibliográficos
Autores principales: Jiang, Shuai, Li, Hao, Hong, Hao, Du, Guifang, Huang, Xin, Sun, Yu, Wang, Junting, Tao, Huan, Xu, Kang, Li, Cheng, Chen, Yang, Chen, Hebing, Bo, Xiaochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138881/
https://www.ncbi.nlm.nih.gov/pubmed/32987404
http://dx.doi.org/10.1093/bib/bbaa210