Cargando…
Spatial density of open chromatin: an effective metric for the functional characterization of topologically associated domains
Topologically associated domains (TADs) are spatial and functional units of metazoan chromatin structure. Interpretation of the interplay between regulatory factors and chromatin structure within TADs is crucial to understand the spatial and temporal regulation of gene expression. However, a computa...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138881/ https://www.ncbi.nlm.nih.gov/pubmed/32987404 http://dx.doi.org/10.1093/bib/bbaa210 |