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Accel-Align: a fast sequence mapper and aligner based on the seed–embed–extend method

BACKGROUND: Improvements in sequencing technology continue to drive sequencing cost towards $100 per genome. However, mapping sequenced data to a reference genome remains a computationally-intensive task due to the dependence on edit distance for dealing with INDELs and mismatches introduced by sequ...

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Detalles Bibliográficos
Autores principales: Yan, Yiqing, Chaturvedi, Nimisha, Appuswamy, Raja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139006/
https://www.ncbi.nlm.nih.gov/pubmed/34016035
http://dx.doi.org/10.1186/s12859-021-04162-z