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Human placental mesenchymal stem cells ameliorate liver fibrosis in mice by upregulation of Caveolin1 in hepatic stellate cells

BACKGROUND: Liver fibrosis (LF) is a common pathological process characterized by the activation of hepatic stellate cells (HSCs) and accumulation of extracellular matrix. Severe LF causes cirrhosis and even liver failure, a major cause of morbidity and mortality worldwide. Transplantation of human...

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Detalles Bibliográficos
Autores principales: Yao, Yunqi, Xia, Zhemin, Cheng, Fuyi, Jang, Qingyuan, He, Jiao, Pan, Cheng, Zhang, Lin, Ye, Yixin, Wang, Yuan, Chen, Shuang, Su, Dongsheng, Su, Xiaolan, Cheng, Lin, Shi, Gang, Dai, Lei, Deng, Hongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139101/
https://www.ncbi.nlm.nih.gov/pubmed/34016164
http://dx.doi.org/10.1186/s13287-021-02358-x