Alzheimer’s pathology causes impaired inhibitory connections and reactivation of spatial codes during spatial navigation

Synapse loss and altered synaptic strength are thought to underlie cognitive impairment in Alzheimer’s disease (AD) by disrupting neural activity essential for memory. While synaptic dysfunction in AD has been well characterized in anesthetized animals and in vitro, it remains unknown how synaptic t...

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Detalles Bibliográficos
Autores principales: Prince, Stephanie M., Paulson, Abigail L., Jeong, Nuri, Zhang, Lu, Amigues, Solange, Singer, Annabelle C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139125/
https://www.ncbi.nlm.nih.gov/pubmed/33882308
http://dx.doi.org/10.1016/j.celrep.2021.109008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139125/
https://www.ncbi.nlm.nih.gov/pubmed/33882308
http://dx.doi.org/10.1016/j.celrep.2021.109008

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