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Alzheimer’s pathology causes impaired inhibitory connections and reactivation of spatial codes during spatial navigation
Synapse loss and altered synaptic strength are thought to underlie cognitive impairment in Alzheimer’s disease (AD) by disrupting neural activity essential for memory. While synaptic dysfunction in AD has been well characterized in anesthetized animals and in vitro, it remains unknown how synaptic t...
Autores principales: | Prince, Stephanie M., Paulson, Abigail L., Jeong, Nuri, Zhang, Lu, Amigues, Solange, Singer, Annabelle C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139125/ https://www.ncbi.nlm.nih.gov/pubmed/33882308 http://dx.doi.org/10.1016/j.celrep.2021.109008 |
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