Experimental Evidence for Enhanced Receptor Binding by Rapidly Spreading SARS-CoV-2 Variants

Rapidly spreading new variants of SARS-CoV-2 carry multiple mutations in the viral spike protein which attaches to the angiotensin converting enzyme 2 (ACE2) receptor on host cells. Among these mutations are amino acid changes N501Y (lineage B.1.1.7, first identified in the UK), and the combination...

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Detalles Bibliográficos
Autores principales: Laffeber, Charlie, de Koning, Kelly, Kanaar, Roland, Lebbink, Joyce H.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd. 2021
Materias:
Fast Track
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139174/
https://www.ncbi.nlm.nih.gov/pubmed/34023401
http://dx.doi.org/10.1016/j.jmb.2021.167058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139174/
https://www.ncbi.nlm.nih.gov/pubmed/34023401
http://dx.doi.org/10.1016/j.jmb.2021.167058

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