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Experimental Evidence for Enhanced Receptor Binding by Rapidly Spreading SARS-CoV-2 Variants
Rapidly spreading new variants of SARS-CoV-2 carry multiple mutations in the viral spike protein which attaches to the angiotensin converting enzyme 2 (ACE2) receptor on host cells. Among these mutations are amino acid changes N501Y (lineage B.1.1.7, first identified in the UK), and the combination...
Autores principales: | Laffeber, Charlie, de Koning, Kelly, Kanaar, Roland, Lebbink, Joyce H.G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s). Published by Elsevier Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139174/ https://www.ncbi.nlm.nih.gov/pubmed/34023401 http://dx.doi.org/10.1016/j.jmb.2021.167058 |
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