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Systemic Transplantation of Adult Multipotent Stem Cells Functionally Rejuvenates Aged Articular Cartilage

Osteoarthritis (OA) is the most common and debilitating joint disease of advanced age and has no universally effective therapy. Here, we demonstrate that systemic transplantation of adult multipotent muscle-derived stem/progenitor cells (MDSPCs)—isolated from young mice—rejuvenates the knee articula...

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Detalles Bibliográficos
Autores principales: Thompson, Seth D., Pichika, Rajeswari, Lieber, Richard L., Budinger, G.R. Scott, Lavasani, Mitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139193/
https://www.ncbi.nlm.nih.gov/pubmed/34094638
http://dx.doi.org/10.14336/AD.2020.1118