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Bone Cells Differentiation: How CFTR Mutations May Rule the Game of Stem Cells Commitment?

Cystic fibrosis (CF)-related bone disease has emerged as a significant comorbidity of CF and is characterized by decreased bone formation and increased bone resorption. Both osteoblast and osteoclast differentiations are impacted by cystic fibrosis transmembrane conductance regulator (CFTR) mutation...

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Detalles Bibliográficos
Autores principales: Dumortier, Claire, Danopoulos, Soula, Velard, Frdric, Al Alam, Denise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139249/
https://www.ncbi.nlm.nih.gov/pubmed/34026749
http://dx.doi.org/10.3389/fcell.2021.611921