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An intramolecular photoswitch can significantly promote photoactivation of Pt(iv) prodrugs

Selective activation of prodrugs at diseased tissue through bioorthogonal catalysis represents an attractive strategy for precision cancer treatment. Achieving efficient prodrug photoactivation in cancer cells, however, remains challenging. Herein, we report two Pt(iv) complexes, designated as rhoda...

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Detalles Bibliográficos
Autores principales: Deng, Zhiqin, Li, Cai, Chen, Shu, Zhou, Qiyuan, Xu, Zoufeng, Wang, Zhigang, Yao, Houzong, Hirao, Hajime, Zhu, Guangyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139284/
https://www.ncbi.nlm.nih.gov/pubmed/34040729
http://dx.doi.org/10.1039/d0sc06839j