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An intramolecular photoswitch can significantly promote photoactivation of Pt(iv) prodrugs
Selective activation of prodrugs at diseased tissue through bioorthogonal catalysis represents an attractive strategy for precision cancer treatment. Achieving efficient prodrug photoactivation in cancer cells, however, remains challenging. Herein, we report two Pt(iv) complexes, designated as rhoda...
Autores principales: | Deng, Zhiqin, Li, Cai, Chen, Shu, Zhou, Qiyuan, Xu, Zoufeng, Wang, Zhigang, Yao, Houzong, Hirao, Hajime, Zhu, Guangyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139284/ https://www.ncbi.nlm.nih.gov/pubmed/34040729 http://dx.doi.org/10.1039/d0sc06839j |
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