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Infection of humanized mice with a novel phlebovirus presented pathogenic features of severe fever with thrombocytopenia syndrome

Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne emerging phlebovirus with high mortality rates of 6.0 to 30%. SFTSV infection is characterized by high fever, thrombocytopenia, leukopenia, hemorrhage and multiple organ failures. Currently, specific therapies and vaccines rem...

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Detalles Bibliográficos
Autores principales: Xu, Shijie, Jiang, Na, Nawaz, Waqas, Liu, Bingxin, Zhang, Fang, Liu, Ye, Wu, Xilin, Wu, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139491/
https://www.ncbi.nlm.nih.gov/pubmed/33974679
http://dx.doi.org/10.1371/journal.ppat.1009587