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Myeloid-derived growth factor inhibits inflammation and alleviates endothelial injury and atherosclerosis in mice

Whether bone marrow modulates systemic metabolism remains unknown. Here, we found that (i) myeloid cell–specific myeloid-derived growth factor (MYDGF) deficiency exacerbated vascular inflammation, adhesion responses, endothelial injury, and atherosclerosis in vivo. (ii) Myeloid cell–specific MYDGF r...

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Detalles Bibliográficos
Autores principales: Meng, Biying, Li, Yixiang, Ding, Yan, Xu, Xiaoli, Wang, Li, Guo, Bei, Zhu, Biao, Zhang, Jiajia, Xiang, Lin, Dong, Jing, Liu, Min, Xiang, Lingwei, Xiang, Guangda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139583/
https://www.ncbi.nlm.nih.gov/pubmed/34020949
http://dx.doi.org/10.1126/sciadv.abe6903