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Adult neural stem cells have latent inflammatory potential that is kept suppressed by Tcf4 to facilitate adult neurogenesis

Inflammation is known to adversely affect adult neurogenesis, wherein the source of inflammation is largely thought to be extraneous to the neurogenic niche. Here, we demonstrate that the adult hippocampal neural progenitors harbor an inflammatory potential that is proactively suppressed by transcri...

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Detalles Bibliográficos
Autores principales: Shariq, Mohammad, Sahasrabuddhe, Vinaya, Krishna, Sreevatsan, Radha, Swathi, Nruthyathi, Bellampalli, Ravishankara, Dwivedi, Anukriti, Cheramangalam, Rajit, Reizis, Boris, Hébert, Jean, Ghosh, Hiyaa S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139598/
https://www.ncbi.nlm.nih.gov/pubmed/34020954
http://dx.doi.org/10.1126/sciadv.abf5606