Direct Priming of CD8(+) T Cells Persists in the Face of Cowpox Virus Inhibitors of Antigen Presentation

Vaccinia virus (VACV) was the vaccine used to eradicate smallpox and is being repurposed as a vaccine vector. CD8(+) T cells are key antiviral mediators but require priming to become effector or memory cells. Priming requires an interaction with dendritic cells that are either infected (direct primi...

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Detalles Bibliográficos
Autores principales: Lin, Leon C. W., Croft, Sarah N., Croft, Nathan P., Wong, Yik Chun, Smith, Stewart A., Tang, Swee-Seong, Purcell, Anthony W., Tscharke, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Pathogenesis and Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139650/
https://www.ncbi.nlm.nih.gov/pubmed/33692206
http://dx.doi.org/10.1128/JVI.00186-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139650/
https://www.ncbi.nlm.nih.gov/pubmed/33692206
http://dx.doi.org/10.1128/JVI.00186-21

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