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Direct Priming of CD8(+) T Cells Persists in the Face of Cowpox Virus Inhibitors of Antigen Presentation

Vaccinia virus (VACV) was the vaccine used to eradicate smallpox and is being repurposed as a vaccine vector. CD8(+) T cells are key antiviral mediators but require priming to become effector or memory cells. Priming requires an interaction with dendritic cells that are either infected (direct primi...

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Detalles Bibliográficos
Autores principales:	Lin, Leon C. W., Croft, Sarah N., Croft, Nathan P., Wong, Yik Chun, Smith, Stewart A., Tang, Swee-Seong, Purcell, Anthony W., Tscharke, David C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Pathogenesis and Immunity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139650/ https://www.ncbi.nlm.nih.gov/pubmed/33692206 http://dx.doi.org/10.1128/JVI.00186-21

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