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Potential Differences in Cleavage of the S Protein and Type 1 Interferon Together Control Human Coronavirus Infection, Propagation, and Neuropathology within the Central Nervous System

Human coronaviruses (HCoV) are respiratory pathogens which have been known since the 1960s. In December 2019, a new betacoronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was reported, and it is responsible for one of the biggest pandemics of the last 2 centuries. Available e...

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Detalles Bibliográficos
Autores principales: Le Coupanec, Alain, Desforges, Marc, Kaufer, Benedikt, Dubeau, Philippe, Côté, Marceline, Talbot, Pierre J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139659/
https://www.ncbi.nlm.nih.gov/pubmed/33627397
http://dx.doi.org/10.1128/JVI.00140-21