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Oncolytic Foamy Virus: Generation and Properties of a Nonpathogenic Replicating Retroviral Vector System That Targets Chronically Proliferating Cancer Cells

Nonpathogenic retroviruses of the Spumaretrovirinae subfamily can persist long term in the cytoplasm of infected cells, completing their life cycle only after the nuclear membrane dissolves at the time of cell division. Since the targeting of slowly dividing cancer cells remains an unmet need in onc...

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Detalles Bibliográficos
Autores principales: Budzik, Karol M., Nace, Rebecca A., Ikeda, Yasuhiro, Russell, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139661/
https://www.ncbi.nlm.nih.gov/pubmed/33692205
http://dx.doi.org/10.1128/JVI.00015-21