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Porcine Sapovirus-Induced Tight Junction Dissociation via Activation of the RhoA/ROCK/MLC Signaling Pathway

Tight junctions (TJs) are a major barrier and also an important portal of entry for different pathogens. Porcine sapovirus (PSaV) induces early disruption of the TJ integrity of polarized LLC-PK cells, allowing it to bind to the buried occludin coreceptors hidden beneath the TJs on the basolateral s...

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Detalles Bibliográficos
Autores principales: Sharif, Muhammad, Baek, Yeong-Bin, Naveed, Ahsan, Stalin, Nattan, Kang, Mun-Il, Park, Sang-Ik, Soliman, Mahmoud, Cho, Kyoung-Oh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139687/
https://www.ncbi.nlm.nih.gov/pubmed/33692204
http://dx.doi.org/10.1128/JVI.00051-21