The Furin-S2′ Site in Avian Coronavirus Plays a Key Role in Central Nervous System Damage Progression

The furin cleavage site plays an important role in virus pathogenicity. The spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) harbors a furin cleavage site insertion, in contrast to SARS-CoV, which may be related to its stronger communicability. An avian coronavirus with...

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Detalles Bibliográficos
Autores principales: Cheng, Jinlong, Zhao, Ye, Hu, Yanxin, Zhao, Jing, Xue, Jia, Zhang, Guozhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Pathogenesis and Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139701/
https://www.ncbi.nlm.nih.gov/pubmed/33727330
http://dx.doi.org/10.1128/JVI.02447-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139701/
https://www.ncbi.nlm.nih.gov/pubmed/33727330
http://dx.doi.org/10.1128/JVI.02447-20

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