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Disruption in A-to-I Editing Levels Affects C. elegans Development More Than a Complete Lack of Editing
A-to-I RNA editing, catalyzed by ADAR proteins, is widespread in eukaryotic transcriptomes. Studies showed that, in C. elegans, ADR-2 can actively deaminate dsRNA, whereas ADR-1 cannot. Therefore, we set out to study the effect of each of the ADAR genes on the RNA editing process. We performed compr...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139731/ https://www.ncbi.nlm.nih.gov/pubmed/31018137 http://dx.doi.org/10.1016/j.celrep.2019.03.095 |