Disruption in A-to-I Editing Levels Affects C. elegans Development More Than a Complete Lack of Editing

A-to-I RNA editing, catalyzed by ADAR proteins, is widespread in eukaryotic transcriptomes. Studies showed that, in C. elegans, ADR-2 can actively deaminate dsRNA, whereas ADR-1 cannot. Therefore, we set out to study the effect of each of the ADAR genes on the RNA editing process. We performed compr...

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Detalles Bibliográficos
Autores principales: Ganem, Nabeel S., Ben-Asher, Noa, Manning, Aidan C., Deffit, Sarah N., Washburn, Michael C., Wheeler, Emily C., Yeo, Gene W., Ben-Naim Zgayer, Orna, Mantsur, Einav, Hundley, Heather A., Lamm, Ayelet T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139731/
https://www.ncbi.nlm.nih.gov/pubmed/31018137
http://dx.doi.org/10.1016/j.celrep.2019.03.095

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