VSIG4(+) peritoneal macrophages induce apoptosis of double-positive thymocyte via the secretion of TNF-α in a CLP-induced sepsis model resulting in thymic atrophy

Thymic atrophy in sepsis is a critical disadvantage because it induces immunosuppression and increases the mortality rate as the disease progresses. However, the exact mechanism of thymic atrophy has not been fully elucidated. In this study, we discovered a novel role for VSIG4-positive peritoneal m...

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Detalles Bibliográficos
Autores principales: Cho, Hae-Yun, Yang, Yun Gyeong, Jeon, Youkyoung, Lee, Chae-Kwan, Choi, InHak, Lee, Soo-Woong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139869/
https://www.ncbi.nlm.nih.gov/pubmed/34023853
http://dx.doi.org/10.1038/s41419-021-03806-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139869/
https://www.ncbi.nlm.nih.gov/pubmed/34023853
http://dx.doi.org/10.1038/s41419-021-03806-5

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