A multiparametric approach to improve the prediction of response to immunotherapy in patients with metastatic NSCLC

BACKGROUND: It is still unclear how to combine biomarkers to identify patients who will truly benefit from anti-PD-1 agents in NSCLC. This study investigates exosomal mRNA expression of PD-L1 and IFN-γ, PD-L1 polymorphisms, tumor mutational load (TML) in circulating cell-free DNA (cfDNA) and radiomi...

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Detalles Bibliográficos
Autores principales: Del Re, Marzia, Cucchiara, Federico, Rofi, Eleonora, Fontanelli, Lorenzo, Petrini, Iacopo, Gri, Nicole, Pasquini, Giulia, Rizzo, Mimma, Gabelloni, Michela, Belluomini, Lorenzo, Crucitta, Stefania, Ciampi, Raffaele, Frassoldati, Antonio, Neri, Emanuele, Porta, Camillo, Danesi, Romano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139911/
https://www.ncbi.nlm.nih.gov/pubmed/33315149
http://dx.doi.org/10.1007/s00262-020-02810-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139911/
https://www.ncbi.nlm.nih.gov/pubmed/33315149
http://dx.doi.org/10.1007/s00262-020-02810-6

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