2,6-diaminopurine promotes repair of DNA lesions under prebiotic conditions

High-yielding and selective prebiotic syntheses of RNA and DNA nucleotides involve UV irradiation to promote the key reaction steps and eradicate biologically irrelevant isomers. While these syntheses were likely enabled by UV-rich prebiotic environment, UV-induced formation of photodamages in polym...

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Detalles Bibliográficos
Autores principales: Szabla, Rafał, Zdrowowicz, Magdalena, Spisz, Paulina, Green, Nicholas J., Stadlbauer, Petr, Kruse, Holger, Šponer, Jiří, Rak, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139960/
https://www.ncbi.nlm.nih.gov/pubmed/34021158
http://dx.doi.org/10.1038/s41467-021-23300-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139960/
https://www.ncbi.nlm.nih.gov/pubmed/34021158
http://dx.doi.org/10.1038/s41467-021-23300-y

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