Cryptic developmental events determine medulloblastoma radiosensitivity and cellular heterogeneity without altering transcriptomic profile

It is unclear why medulloblastoma patients receiving similar treatments experience different outcomes. Transcriptomic profiling identified subgroups with different prognoses, but in each subgroup, individuals remain at risk of incurable recurrence. To investigate why similar-appearing tumors produce...

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Detalles Bibliográficos
Autores principales: Malawsky, Daniel Shiloh, Weir, Seth J., Ocasio, Jennifer Karin, Babcock, Benjamin, Dismuke, Taylor, Cleveland, Abigail H., Donson, Andrew M., Vibhakar, Rajeev, Wilhelmsen, Kirk, Gershon, Timothy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139976/
https://www.ncbi.nlm.nih.gov/pubmed/34021242
http://dx.doi.org/10.1038/s42003-021-02099-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139976/
https://www.ncbi.nlm.nih.gov/pubmed/34021242
http://dx.doi.org/10.1038/s42003-021-02099-w

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