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Super-resolution imaging reveals α-synuclein seeded aggregation in SH-SY5Y cells

Aggregation of α-synuclein (α-syn) is closely linked to Parkinson’s disease (PD) and the related synucleinopathies. Aggregates spread through the brain during the progression of PD, but the mechanism by which this occurs is still not known. One possibility is a self-propagating, templated-seeding me...

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Detalles Bibliográficos
Autores principales: Sang, Jason C., Hidari, Eric, Meisl, Georg, Ranasinghe, Rohan T., Spillantini, Maria Grazia, Klenerman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139990/
https://www.ncbi.nlm.nih.gov/pubmed/34021258
http://dx.doi.org/10.1038/s42003-021-02126-w