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Super-resolution imaging reveals α-synuclein seeded aggregation in SH-SY5Y cells
Aggregation of α-synuclein (α-syn) is closely linked to Parkinson’s disease (PD) and the related synucleinopathies. Aggregates spread through the brain during the progression of PD, but the mechanism by which this occurs is still not known. One possibility is a self-propagating, templated-seeding me...
Autores principales: | Sang, Jason C., Hidari, Eric, Meisl, Georg, Ranasinghe, Rohan T., Spillantini, Maria Grazia, Klenerman, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139990/ https://www.ncbi.nlm.nih.gov/pubmed/34021258 http://dx.doi.org/10.1038/s42003-021-02126-w |
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