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Co-development of central and peripheral neurons with trunk mesendoderm in human elongating multi-lineage organized gastruloids

Stem cell technologies including self-assembling 3D tissue models provide access to early human neurodevelopment and fundamental insights into neuropathologies. Gastruloid models have not been used to investigate co-developing central and peripheral neuronal systems with trunk mesendoderm which we a...

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Detalles Bibliográficos
Autores principales: Olmsted, Zachary T., Paluh, Janet L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140076/
https://www.ncbi.nlm.nih.gov/pubmed/34021144
http://dx.doi.org/10.1038/s41467-021-23294-7