Multiscale-omic assessment of EWSR1-NFATc2 fusion positive sarcomas identifies the mTOR pathway as a potential therapeutic target

Sarcomas harboring EWSR1-NFATc2 fusions have historically been categorized and treated as Ewing sarcoma. Emerging evidence suggests unique molecular characteristics and chemotherapy sensitivities in EWSR1-NFATc2 fusion positive sarcomas. Comprehensive genomic profiles of 1024 EWSR1 fusion positive s...

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Detalles Bibliográficos
Autores principales: Seligson, Nathan D., Maradiaga, Richard D., Stets, Colin M., Katzenstein, Howard M., Millis, Sherri Z., Rogers, Alan, Hays, John L., Chen, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140100/
https://www.ncbi.nlm.nih.gov/pubmed/34021224
http://dx.doi.org/10.1038/s41698-021-00177-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140100/
https://www.ncbi.nlm.nih.gov/pubmed/34021224
http://dx.doi.org/10.1038/s41698-021-00177-0

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