Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2

Nuclear import of RNA polymerase II (Pol II) involves the conserved factor RPAP2. Here we report the cryo-electron microscopy (cryo-EM) structure of mammalian Pol II in complex with human RPAP2 at 2.8 Å resolution. The structure shows that RPAP2 binds between the jaw domains of the polymerase subuni...

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Detalles Bibliográficos
Autores principales: Fianu, Isaac, Dienemann, Christian, Aibara, Shintaro, Schilbach, Sandra, Cramer, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140126/
https://www.ncbi.nlm.nih.gov/pubmed/34021257
http://dx.doi.org/10.1038/s42003-021-02088-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140126/
https://www.ncbi.nlm.nih.gov/pubmed/34021257
http://dx.doi.org/10.1038/s42003-021-02088-z

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