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Transcriptome-wide association study uncovers the role of essential genes in anthracycline-induced cardiotoxicity

Anthracyclines are highly effective chemotherapeutic agents; however, their clinical utility is limited by severe anthracycline-induced cardiotoxicity (ACT). Genome-wide association studies (GWAS) have uncovered several genetic variants associated with ACT, but the impact of these findings requires...

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Detalles Bibliográficos
Autores principales: Scott, Erika N., Wright, Galen E. B., Drögemöller, Britt I., Hasbullah, Jafar S., Gunaretnam, Erandika P., Miao, Fudan, Bhavsar, Amit P., Shen, Fei, Schneider, Bryan P., Carleton, Bruce C., Ross, Colin J. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140137/
https://www.ncbi.nlm.nih.gov/pubmed/34021165
http://dx.doi.org/10.1038/s41525-021-00199-4