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Fluorescence Fluctuation Spectroscopy enables quantification of potassium channel subunit dynamics and stoichiometry

Voltage-gated potassium (Kv) channels are a family of membrane proteins that facilitate K(+) ion diffusion across the plasma membrane, regulating both resting and action potentials. Kv channels comprise four pore-forming α subunits, each with a voltage sensing domain, and they are regulated by inter...

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Detalles Bibliográficos
Autores principales: Tedeschi, Giulia, Scipioni, Lorenzo, Papanikolaou, Maria, Abbott, Geoffrey W., Digman, Michelle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140153/
https://www.ncbi.nlm.nih.gov/pubmed/34021177
http://dx.doi.org/10.1038/s41598-021-90002-2