Therapeutic Assessment of Combination Therapy with a Neprilysin Inhibitor and Angiotensin Type 1 Receptor Antagonist on Angiotensin II–Induced Atherosclerosis, Abdominal Aortic Aneurysms, and Hypertension

Combined neprilysin (NEP) inhibition (sacubitril) and angiotensin type 1 receptor (AT1R) antagonism (valsartan) is used in the treatment of congestive heart failure and is gaining interest for other angiotensin II (AngII)-related cardiovascular diseases. In addition to heart failure, AngII promotes...

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Detalles Bibliográficos
Autores principales: AlSiraj, Yasir, Thatcher, Sean E., Liang, Ching Ling, Ali, Heba, Ensor, Mark, Cassis, Lisa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2021
Materias:
Cardiovascular
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140395/
https://www.ncbi.nlm.nih.gov/pubmed/33707301
http://dx.doi.org/10.1124/jpet.121.000525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140395/
https://www.ncbi.nlm.nih.gov/pubmed/33707301
http://dx.doi.org/10.1124/jpet.121.000525

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