Role of the ABL tyrosine kinases in the epithelial–mesenchymal transition and the metastatic cascade

The ABL kinases, ABL1 and ABL2, promote tumor progression and metastasis in various solid tumors. Recent reports have shown that ABL kinases have increased expression and/or activity in solid tumors and that ABL inactivation impairs metastasis. The therapeutic effects of ABL inactivation are due in...

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Detalles Bibliográficos
Autores principales: Luttman, Jillian Hattaway, Colemon, Ashley, Mayro, Benjamin, Pendergast, Ann Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140471/
https://www.ncbi.nlm.nih.gov/pubmed/34022881
http://dx.doi.org/10.1186/s12964-021-00739-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140471/
https://www.ncbi.nlm.nih.gov/pubmed/34022881
http://dx.doi.org/10.1186/s12964-021-00739-6

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