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Annexin A1 protects against cerebral ischemia–reperfusion injury by modulating microglia/macrophage polarization via FPR2/ALX-dependent AMPK-mTOR pathway

BACKGROUND: Cerebral ischemia–reperfusion (I/R) injury is a major cause of early complications and unfavorable outcomes after endovascular thrombectomy (EVT) therapy in patients with acute ischemic stroke (AIS). Recent studies indicate that modulating microglia/macrophage polarization and subsequent...

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Detalles Bibliográficos
Autores principales: Xu, Xin, Gao, Weiwei, Li, Lei, Hao, Jiheng, Yang, Bin, Wang, Tao, Li, Long, Bai, Xuesong, Li, Fanjian, Ren, Honglei, Zhang, Meng, Zhang, Liyong, Wang, Jiyue, Wang, Dong, Zhang, Jianning, Jiao, Liqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140477/
https://www.ncbi.nlm.nih.gov/pubmed/34022892
http://dx.doi.org/10.1186/s12974-021-02174-3