Cargando…
Annexin A1 protects against cerebral ischemia–reperfusion injury by modulating microglia/macrophage polarization via FPR2/ALX-dependent AMPK-mTOR pathway
BACKGROUND: Cerebral ischemia–reperfusion (I/R) injury is a major cause of early complications and unfavorable outcomes after endovascular thrombectomy (EVT) therapy in patients with acute ischemic stroke (AIS). Recent studies indicate that modulating microglia/macrophage polarization and subsequent...
Autores principales: | Xu, Xin, Gao, Weiwei, Li, Lei, Hao, Jiheng, Yang, Bin, Wang, Tao, Li, Long, Bai, Xuesong, Li, Fanjian, Ren, Honglei, Zhang, Meng, Zhang, Liyong, Wang, Jiyue, Wang, Dong, Zhang, Jianning, Jiao, Liqun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140477/ https://www.ncbi.nlm.nih.gov/pubmed/34022892 http://dx.doi.org/10.1186/s12974-021-02174-3 |
Ejemplares similares
-
Annexin A1 Interaction with the FPR2/ALX Receptor: IDENTIFICATION OF DISTINCT DOMAINS AND DOWNSTREAM ASSOCIATED SIGNALING
por: Bena, Stefania, et al.
Publicado: (2012) -
Targeting the Annexin A1-FPR2/ALX pathway for host-directed therapy in dengue disease
por: Costa, Vivian Vasconcelos, et al.
Publicado: (2022) -
Annexin A1-FPR2/ALX Signaling Axis Regulates Acute Inflammation during Chikungunya Virus Infection
por: de Araújo, Simone, et al.
Publicado: (2022) -
Inflammation and Cancer: Role of Annexin A1 and FPR2/ALX in Proliferation and Metastasis in Human Laryngeal Squamous Cell Carcinoma
por: Gastardelo, Thaís Santana, et al.
Publicado: (2014) -
ALX/FPR2 Modulates Anti-Inflammatory Responses in Mouse Submandibular Gland
por: Wang, Ching-Shuen, et al.
Publicado: (2016)