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Fibroblast dedifferentiation as a determinant of successful regeneration

Limb regeneration, while observed lifelong in salamanders, is restricted in post-metamorphic Xenopus laevis frogs. Whether this loss is due to systemic factors or an intrinsic incapability of cells to form competent stem cells has been unclear. Here, we use genetic fate mapping to establish that con...

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Detalles Bibliográficos
Autores principales: Lin, Tzi-Yang, Gerber, Tobias, Taniguchi-Sugiura, Yuka, Murawala, Prayag, Hermann, Sarah, Grosser, Lidia, Shibata, Eri, Treutlein, Barbara, Tanaka, Elly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140481/
https://www.ncbi.nlm.nih.gov/pubmed/34004152
http://dx.doi.org/10.1016/j.devcel.2021.04.016