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Fibroblast dedifferentiation as a determinant of successful regeneration
Limb regeneration, while observed lifelong in salamanders, is restricted in post-metamorphic Xenopus laevis frogs. Whether this loss is due to systemic factors or an intrinsic incapability of cells to form competent stem cells has been unclear. Here, we use genetic fate mapping to establish that con...
Autores principales: | Lin, Tzi-Yang, Gerber, Tobias, Taniguchi-Sugiura, Yuka, Murawala, Prayag, Hermann, Sarah, Grosser, Lidia, Shibata, Eri, Treutlein, Barbara, Tanaka, Elly M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140481/ https://www.ncbi.nlm.nih.gov/pubmed/34004152 http://dx.doi.org/10.1016/j.devcel.2021.04.016 |
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